Search our team at AdventHealth Research Institute
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NCT04321031
Prospective Observational Study to Assess Outcomes in Pediatric Liver Transplant Recipients
This study is not currently enrolling.Associated Conditions: TransplantResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThe purpose of the study is to collect scientific data on pediatric liver transplantation to learn more about how children do after liver transplant. Collecting this data is expected to help...
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NCT04321031
STARZL NETWORK FOR EXCELLENCE IN PEDIATRIC TRANSPLANTATION (snept) to improve the health of pediatric LIVER TRANSPLANT PATIENTS
This study is currently enrolling.Associated Conditions: Liver DiseaseResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaPediatric liver transplantation has become the standard of care for many children with liver diseases. However, different institutions often treat and manage children with liver transplant in...
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NCT06414603
23-069-TRP: A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy (ACES-EMB)
This study is currently enrolling.Associated Conditions: Heart Transplant RejectionResearch Area: Transplant ResearchResearch Location: Orlando, FloridaA Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance with Cell-free DNA versus Endomyocardial Biopsy
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NCT05654922
A Phase 3, Open-Label, Randomized, Standard of Care- Controlled, Parallel Arm Study to Demonstrate Efficacy and Safety of ARINA-1 in the Prevention of Bronchiolitis Obliterans Syndrome Progression in Participants with Bilateral Lung Transplant
This study is currently enrolling.Research Area: Transplant ResearchResearch Location: Orlando, FloridaThe purpose of this research study is to see if the investigational drug, ARINA-1 when used with the investigational PARI eFlow nebulizer system, can stabilize or improve the lung function of...
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NCT01351545
A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) for transplantation in pediatric and adult patients with hematologic malignancies and other indications
This study is not currently enrolling.Associated Conditions: Blood Diseases and DisordersResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThe primary purposes of this study are to: (a) Provide access to cord blood units for recipients whose best choice for a cord blood unit(s) do not meet all FDA standards, but do meet standards set by...
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NCT05457556
A Multi-Center, Phase 3, Randomized Trial of Matched Unrelated Donor (MUD) versus HLA-Haploidentical Related (Haplo) Myeloablative Hematopoietic Cell Transplantation for Children, Adolescents, and Young Adults (AYA) with Acute Leukemia or Myelodysplastic Syndrome (MDS)
This study is currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaYou are being asked to take part in this research study because you have been diagnosed with acute leukemia or myelodysplastic syndrome (MDS).
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NCT04836390
A Phase II Pilot Study of Donor-Derived Ex-VivoExpanded Natural Killer Cell Infusions in Childrenand Young Adults with High-Risk Acute Myeloid Leukemia Receiving Myeloablative HLA Haploidentical Hematopoietic Cell Transplant: A Multicenter Pediatric Transplantation and Cellular Therapy Consortium (PTCTC) Study (EXCEL Trial) PTCTC CT2001.
This study is currently enrolling.Associated Conditions: LeukemiaResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaParticipants will be invited to join this study if they have a blood disease called acute myeloid leukemia (AML) and it has been decided that they need a transplant as part of their treatment plan....
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NCT04071457
S1803, Phase III Study of Daratumumab/rHuPH20 (NSC-810307) + Lenalidomide or Lenalidomide as Post-Autologous Stem Cell Transplant Maintenance Therapy in Patients with Multiple Myeloma (MM) Using Minimal Residual Disease to Direct Therapy Duration (DRAMMATIC Study)
This study is currently enrolling.Research Area: Rocky Mountain Cancer ResearchPatients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first...
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Treatment of Bone Marrow Failure, Post Allogeneic Bone Marrow Transplant,w ith CD34+ Cell-Enriched Hematopoietic Stem Cell Infusion (Miltenyi Biotec's CliniMACS CD34 Reagent System) A HDE Treatment Protocol
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer Research[Shell Only] - HUD/CUD.
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North American Pediatric Renal Trials Collaborative Studies (NAPRTCS)
This study is currently enrolling.Associated Conditions: TransplantResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaNAPRTCS is a research effort that was organized in 1987 by a group of physicians and surgeons committed to the success of pediatric renal transplant.
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A global Phase 3, open label, Randomized Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy vs the standard of care treatment in adult patients with high-risk, transplant-eligible Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma (ANTLER-Phase 3 [Part III])
This study is not currently enrolling.Associated Conditions: Bone CancerResearch Area: Clinical Cancer Research -
NCT05940857
Sponsor-Initiated OCS Liver Perfusion (OLP-II) Registry
This study is currently enrolling.Research Area: Transplant ResearchResearch Location: Orlando, FloridaThe objective of the sponsor-initiated OLP-II Registry is to collect data on the post-transplant clinical outcomes of donor livers preserved and assessed on OCS Liver System and to document...