Search our team at AdventHealth Research Institute
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NCT03962543
A Phase 2b Trial of the MEK 1/2 Inhibitor (MEKi) PD-0325901 in Adult and Pediatric Patients with Neurofibromatosis Type 1 (NF1)-Associated Inoperable Plexiform Neurofibromas (PNs) that are Progressing or Causing Significant Morbidity
This study is currently enrolling.Associated Conditions: NeurofibromatosisResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThis research is conducted to study an investigational drug referred to as PD-0325901 (also known as mirdametinib) that has not been approved by the US Food and Drug Administration (FDA) or any other...
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NCT03334292
Natural History of Wilson Disease: Registry for Patients with Wilson Disease
This study is currently enrolling.Associated Conditions: Wilson’s DiseaseResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaYou are invited to donate your blood, urine, research data, and related information to be stored (banked) in a research specimen/data database or bank where it can be used for future research projects...
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North American Pediatric Renal Trials Collaborative Studies (NAPRTCS)
This study is currently enrolling.Associated Conditions: TransplantResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaNAPRTCS is a research effort that was organized in 1987 by a group of physicians and surgeons committed to the success of pediatric renal transplant.
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NCT06639958
Risk-Based 6MP Adherence Enhancement Strategies in Children, Adolescent and Young Adults With ALL - A Pilot Study Study Sponsor: Children’s Oncology Group
This study is not currently enrolling.Research Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThis study is being done to answer the following question: Can we help children, adolescents and young adults with ALL to remember to take their daily Maintenance medicine, 6MP, at home? We are doing...
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NCT05457556
A Feasibility and Randomized Phase 2/3 Study of the VEFGR2/MET Inhibitor Cabozantinib in Combination with Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma
This study is not currently enrolling.Associated Conditions: Bone CancerResearch Area: Pediatric Research and Clinical TrialsThis study looks at how well cabozantinib in combination with MAP work when given to children and young adults with newly diagnosed OST disease. Cabozantinib is experimental because it has not been...
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NCT05945433
Anova Surgical System – Registry Study
This study is not currently enrolling.Research Area: Pediatric Research and Clinical TrialsYou are invited to take part in a patient registry research study. A patient registry is an organized way to collect observational data from a large group of patients undergoing the same procedure...
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NCT04223752
A Phase 1, open-label, non-comparative, multicenter clinical study to evaluate the safety, tolerability, and pharmacokinetics of ceftolozane/tazobactam (MK-7625A) in pediatric participants with nosocomial pneumonia
This study is not currently enrolling.Research Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaCeftolozane/tazobactam, also known as Zerbaxa, is a combination product, and is available by prescription for use in adults for the treatment of complicated urinary tract infections, including...
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Donor Breast Milk and Serum Ferritin Levels in Very Preterm Infants: A Prospective, Observational Study
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThe purpose of the study is to compare the iron levels in very preterm infants receiving donor breast milk (DBM) to very preterm infants receiving maternal breast milks (MBM).
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Conservative Fluid Management in the First Week of Life Reduces the Risk of Prolonged Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants
This study is not currently enrolling.Research Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaTo retrospectively collect and analyze the data to show that a change in practice at the AdventHealth Orlando Neonatal Intensive Care Unit (NICU), implementing conservative fluid intake during the...
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NCT03321734
INTERMITTENT HYPOXIA AND CAFFEINE IN INFANTS BORN PRETERM
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaYou are being asked to allow your baby to be in this research study because your premature baby was given the medication caffeine as treatment for his/her immature breathing in the neonatal intensive...
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NCT04185363
An Open-label Extension Study to Evaluate the Long-term Safety and Efficacy of Maralixibat in the Treatment of Subjects with Progressive Familial Intrahepatic Cholestasis (PFIC)
This study is not currently enrolling.Associated Conditions: Wilsons DiseaseResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaThe primary objective of the study is to evaluate the long-term safety and tolerability of maralixibat. Secondary objectives: To evaluate the long-term efficacy of maralixibat, including the...
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Mother Providing Recorded Voice to Her Preterm Infant in Incubator Improves Her Own Grief and Emotional Status
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaStudies have shown that infants prefer the sound of their mother's voice above all others. After 2 weeks (or 14 days) of life, we would like to begin playing a recording to babies of their mother's...